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Graphical

VesicleAutolysosomeAutophagosomeCytoplasmic vesicleLysosome

Definition

The autolysosome is a single-membrane organelle resulting from the fusion of a double-membrane autophagosome with a lysosome during macroautophagy. The outer membrane of the autophagosome fuses with the lysosome membrane whereas the inner membrane and the autophagic cargo are released into the lumen and degraded. Alternatively, the convergence of macroautophagy and endocytosis produces a single-membrane amphisome that also results in an autolysosome upon fusion with a lysosome.

Synonyms

Degrading autophagic vacuole

Category

› Cellular component
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