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Entry version 87 (07 Apr 2021)
Sequence version 1 (10 Jan 2006)
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Protein

Magnetosome formation protease MamE

Gene

mamE

Organism
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation (PubMed:21414040). Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable) (PubMed:26981620). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome (PubMed:20212111, PubMed:21414040).1 Publication3 Publications

Miscellaneous

This bacteria makes up to 20 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe3O4).Curated
There are 2 paralogous genes in the genome; limE (amb1002) has a partially overlapping function with MamE, while mamE-like (amb0410) does not seem to play a role in biomineralization.1 Publication
Expression of just the minimal mamAB gene cluster (amb0961 to amb0978), including this gene, is sufficient to form a minimal magnetosome chain with small magnetite particles.1 Publication
There is a third MCR motif in the M.gryphiswaldense strain MSR-1 MamE ortholog.Curated

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

heme2 PublicationsNote: Probably binds 2 heme groups via the 2 magnetochrome (MCR) motifs.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Autoproteolysis is stimulated by exogenous substrates or peptides that bind to its PDZ domains; may be stimulated by an environmental cue in vivo. Protease activity is tightly regulated; increasing its activity decreases substrate levels and disturbs biomineralization.1 Publication

Redox potential

E0 is -32 mV.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei188Charge relay systemBy similarity1 Publication1 Publication1
Active sitei221Charge relay systemBy similarity1 Publication1 Publication1
Active sitei297Charge relay systemBy similarity1 Publication1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei392Heme 1; covalentPROSITE-ProRule annotation2 Publications1
Binding sitei395Heme 1; covalentPROSITE-ProRule annotation2 Publications1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi396Iron 1 (heme axial ligand)PROSITE-ProRule annotation2 Publications1
Binding sitei438Heme 2; covalent2 Publications1
Binding sitei441Heme 2; covalent2 Publications1
Metal bindingi442Iron 2 (heme axial ligand)2 Publications1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease
Biological processBiomineralization
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MMAG342108:G1G2B-993-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Magnetosome formation protease MamECurated (EC:3.4.21.-1 Publication)
Alternative name(s):
Magnetochrome MamECurated
Magnetosome serine protease MamECurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mamE
Ordered Locus Names:amb0963
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMagnetospirillum magneticum (strain AMB-1 / ATCC 700264)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri342108 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeMagnetospirillum
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007058 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 21CytoplasmicCuratedAdd BLAST21
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Topological domaini43 – 728Lumenal1 PublicationAdd BLAST686

Keywords - Cellular componenti

Magnetosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells have no magnetic response but still make empty magnetosome membranes. Alterations in localization of magnetosome proteins; MamA is mislocalized to random foci near the cell membrane, while MamJ is more diffuse than in wild-type (PubMed:20212111). Alterations in localization of magnetosome proteins MamC, MamF and MamI (PubMed:21414040). Deletion of genes mamH to mamV (amb0961 to amb0978) gives cells with no magnetosomes and no magnetic response (PubMed:20212111).2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi188H → A: Some loss of magnetic response; when associated with A-221 and A-297. Significant loss of magnetic response, MamE, MamO, MamP no longer processed when amb1002 to amb1007 are also deleted; when associated with A-221 and A-297. 2 Publications1
Mutagenesisi221D → A: Some loss of magnetic response; when associated with A-188 and A-297. Significant loss of magnetic response, MamE, MamO, MamP no longer processed when amb1002 to amb1007 are also deleted; when associated with A188 and A-297. 1 Publication1
Mutagenesisi294Q → P: Increased protease activity, decreased dependency on MamO, magnetic response lower than wild-type but higher than deletion mutant. 1 Publication1
Mutagenesisi297S → A: Loss of protease activity. Some loss of magnetic response; when associated with A-188 and A-221. Significant loss of magnetic response, MamE, MamO, MamP no longer processed when amb1002 to amb1007 are also deleted; when associated with A188 and A-221. 2 Publications1
Mutagenesisi392 – 441CTTCH…NCANC → ATTAHDLIPAGNGRPAPMMP IAAPIPPPPIPMGAVSPHTD GRQNMNAANA: Removes both putative heme-binding sites, partial loss of magnetic response, significant loss of magnetic response when amb1002 to amb1007 are also deleted. The latter mutant is capable of making nearly wild-type size crystals, but makes them less frequently and later than wild-type. 1 PublicationAdd BLAST50

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004477791 – 728Magnetosome formation protease MamEAdd BLAST728

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Subject to autocatalytic cleavage; cleavage also requires MamO.1 Publication

Keywords - PTMi

Autocatalytic cleavage

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Expressed during exponential phase in static growth conditions (PubMed:20161777). Part of the probable 18 gene mamAB operon (Probable).1 Publication1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Might interact with MamB via PDZ1.

By similarity

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini471 – 573PDZ 1PROSITE-ProRule annotationAdd BLAST103
Domaini622 – 721PDZ 2PROSITE-ProRule annotationAdd BLAST100

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi375 – 398MCR (magnetochrome) 11 PublicationAdd BLAST24
Motifi421 – 444MCR 21 PublicationAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the peptidase S1C family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_020120_1_0_5

Identification of Orthologs from Complete Genome Data

More...
OMAi
CENCHQI

Database of Orthologous Groups

More...
OrthoDBi
741829at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.42.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009056, Cyt_c-like_dom
IPR040963, MCR
IPR011031, Multihaem_cyt
IPR036280, Multihaem_cyt_sf
IPR001478, PDZ
IPR041489, PDZ_6
IPR036034, PDZ_sf
IPR009003, Peptidase_S1_PA
IPR001940, Peptidase_S1C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18509, MCR, 2 hits
PF17820, PDZ_6, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00834, PROTEASES2C

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228, PDZ, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48695, SSF48695, 1 hit
SSF50156, SSF50156, 2 hits
SSF50494, SSF50494, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51007, CYTC, 1 hit
PS51008, MULTIHEME_CYTC, 1 hit
PS50106, PDZ, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2W8Q8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMFNGDVED GGRGDASCGK DLKRYLMLMG VVALVVLFGA FIYRQSSGGL
60 70 80 90 100
RLGAMLEQMG RGTGPAVNVP VQQGGPSAAV NPAMSVPAGA RVAPPSAAGA
110 120 130 140 150
IATMPPMVDF GPAPIGAGGP FSSVVTLLRN SVVAVTASSA NGQAMPDPLG
160 170 180 190 200
LANPDGLPHF ANPATRSVEN IGTGVIVRND GFIVTNYHVV RGANSVFVTV
210 220 230 240 250
QDDVGSTRYS AEIIKMDEAL DLALLKVAPK TPLTAAVLGD SDGVQVADEV
260 270 280 290 300
IAIGTPFGLD MTVSRGIISA KRKSMVIEGV THSNLLQTDA AINQGNSGGP
310 320 330 340 350
LVISNGTVVG INTAIYTPNG AFAGIGFAVP SNQARLFILD EVGWLPTSTA
360 370 380 390 400
EGASMGLVAM QRPMGGGVGA AGPAIFAGTR APHTDGRQNM DCTTCHDLIP
410 420 430 440 450
AGNGRPAPMM PIAAPIPPPP IPMGAVSPHT DGRQNMNCAN CHQMLGGAAP
460 470 480 490 500
IAAPGLGGGA YRFAQPPGSL AINIQGPRGG QSTAAGTGRV TLLGAALTPM
510 520 530 540 550
SQRLGAQTGV PVGRGVFISG VTPNTPAATA GLRPGDVLLK VDGRPVRLPE
560 570 580 590 600
EVSAIMVEMH AGRSVRLGVL RDGDVRNMTL VAGPAGLAAA AVQAPAIADM
610 620 630 640 650
AQPPMGGMAP TAPGMVAVPG GPAVMPKPPT EFNWLGMEIE TFQAPRPITG
660 670 680 690 700
VPGAVPVPGA KGAQVAEVLV GSRAAVAGLQ ANDLILEVNN RPVAGPARLD
710 720
AAIKGATNAG QQILLKVNRN GQEFWIVL
Length:728
Mass (Da):73,478
Last modified:January 10, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA396F0AE33C69E0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP007255 Genomic DNA Translation: BAE49767.1

NCBI Reference Sequences

More...
RefSeqi
WP_011383396.1, NC_007626.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAE49767; BAE49767; amb0963

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mag:amb0963

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007255 Genomic DNA Translation: BAE49767.1
RefSeqiWP_011383396.1, NC_007626.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiBAE49767; BAE49767; amb0963
KEGGimag:amb0963

Phylogenomic databases

HOGENOMiCLU_020120_1_0_5
OMAiCENCHQI
OrthoDBi741829at2

Enzyme and pathway databases

BioCyciMMAG342108:G1G2B-993-MONOMER

Family and domain databases

Gene3Di2.30.42.10, 2 hits
InterProiView protein in InterPro
IPR009056, Cyt_c-like_dom
IPR040963, MCR
IPR011031, Multihaem_cyt
IPR036280, Multihaem_cyt_sf
IPR001478, PDZ
IPR041489, PDZ_6
IPR036034, PDZ_sf
IPR009003, Peptidase_S1_PA
IPR001940, Peptidase_S1C
PfamiView protein in Pfam
PF18509, MCR, 2 hits
PF17820, PDZ_6, 2 hits
PRINTSiPR00834, PROTEASES2C
SMARTiView protein in SMART
SM00228, PDZ, 2 hits
SUPFAMiSSF48695, SSF48695, 1 hit
SSF50156, SSF50156, 2 hits
SSF50494, SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS51007, CYTC, 1 hit
PS51008, MULTIHEME_CYTC, 1 hit
PS50106, PDZ, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAME_MAGSA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2W8Q8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 18, 2019
Last sequence update: January 10, 2006
Last modified: April 7, 2021
This is version 87 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
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